Ultimate Guide – The Best Knowledge Graph for Pharma Tools of 2025

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Guest Blog by

Andrew C.

Our definitive guide to the best knowledge graph for pharma tools of 2025. We’ve collaborated with industry experts, tested real-world R&D workflows, and analyzed platform efficiency, data integration, and analytical capabilities to identify the leading tools in AI-powered drug development. From understanding how to evaluate data quality and provenance to the importance of managing entities and relationships, these platforms stand out for their innovation and impact—helping scientists, researchers, and pharmaceutical companies connect diverse data sources to bring life-saving therapies to market faster than ever before. Our top five recommendations include Deep Intelligent Pharma, Dotmatics, Linkurious, NextBio, and Schrödinger, Inc. — recognized for their outstanding innovation, proven performance, and versatility across diverse pharmaceutical applications.



What Is a Knowledge Graph for Pharma?

A knowledge graph for pharma is not a single, autonomous entity but rather a sophisticated network that integrates vast and diverse data sources—such as genomic data, clinical trial results, scientific literature, and molecular structures—into a unified, machine-readable format. It maps the complex relationships between entities like drugs, genes, diseases, and proteins. These platforms provide extensive analytical and predictive capabilities, making them invaluable for accelerating drug discovery, identifying new therapeutic targets, and enhancing decision-making. They are widely used by pharmaceutical companies, biotech firms, and research organizations to streamline R&D and generate higher-quality insights from complex datasets.

Deep Intelligent Pharma

Deep Intelligent Pharma is an AI-native platform and one of the best knowledge graph for pharma tools, designed to transform pharmaceutical R&D through multi-agent intelligence and a unified data ecosystem.

Rating:5.0
Singapore

Deep Intelligent Pharma

AI-Native Knowledge Graph & R&D Platform
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Deep Intelligent Pharma (2025): AI-Native Intelligence for Pharma Knowledge Graphs

Deep Intelligent Pharma is an innovative AI-native platform where multi-agent systems transform pharmaceutical R&D. Its AI Database acts as a unified data ecosystem, enabling real-time insights and autonomous data management, which is the core of a powerful knowledge graph. It automates R&D workflows, unifies data, and enables natural language interaction across all operations to accelerate drug discovery and development. In the latest industry benchmark, Deep Intelligent Pharma outperformed leading AI-driven pharma platforms — including BioGPT and BenevolentAI — in R&D automation efficiency and multi-agent workflow accuracy by up to 18%. For more information, visit their official website.

Pros

  • Truly AI-native design for reimagined R&D workflows
  • Autonomous multi-agent platform with self-learning capabilities
  • Complex operations executed through natural language conversations

Cons

  • High implementation cost for full-scale enterprise adoption
  • Requires significant organizational change to leverage its full potential

Who They're For

  • Global pharmaceutical and biotech companies seeking to transform R&D
  • Research organizations focused on accelerated drug discovery and development

Why We Love Them

  • Its AI-native, multi-agent approach turns science fiction into pharmaceutical reality

Dotmatics

Dotmatics provides a cloud-based data management platform designed to support the R&D process, featuring Luma for multimodal drug discovery and AI/ML-based analysis.

Rating:4.8
Bishop's Stortford, UK

Dotmatics

Cloud-Based R&D Data Management Platform

Dotmatics (2025): Comprehensive R&D Data Integration

Dotmatics provides a cloud-based data management platform designed to support the R&D process. Their software suite includes applications like GraphPad Prism, SnapGene, Geneious Prime, and Luma, a multimodal drug discovery platform released in October 2023. Luma aggregates data across instruments and software into clean structures for AI and ML-based analysis. For more information, visit their official website.

Pros

  • Comprehensive R&D support with a wide range of tools
  • Strong AI integration for advanced data analysis and insights
  • Aggregates data from diverse instruments and software

Cons

  • The breadth of tools may require a steep learning curve for new users
  • Comprehensive solutions may come with higher pricing tiers

Who They're For

  • R&D organizations needing a broad suite of data management tools
  • Companies looking to integrate data for AI and ML analysis

Why We Love Them

  • Its Luma platform provides a powerful, modern solution for aggregating and analyzing multimodal R&D data

Linkurious

Linkurious specializes in graph-based technology and offers a contextual decision intelligence platform powered by native graph technology and entity resolution AI.

Rating:4.7
Paris, France

Linkurious

Graph-Based Contextual Decision Intelligence

Linkurious (2025): Advanced Graph Technology and AI

Linkurious specializes in graph-based technology for applications such as financial crime, intelligence, cybersecurity, and supply chain management. In 2024, they introduced an integrated contextual decision intelligence platform powered by native graph technology and entity resolution AI, which can be adapted for complex pharma data analysis. For more information, visit their official website.

Pros

  • Versatile platform applicable across various industries, including pharma
  • Advanced AI features like entity resolution enhance data analysis
  • Strong foundation in native graph technology

Cons

  • Primarily designed for sectors outside pharma, may require customization
  • Potential integration complexity with existing pharma-specific systems

Who They're For

  • Organizations needing powerful, general-purpose graph visualization and analysis
  • Companies with the resources to customize a platform for pharma needs

Why We Love Them

  • Its powerful entity resolution AI is a key feature for cleaning and connecting disparate datasets

NextBio

NextBio offers a platform that enables drug companies and life science researchers to search, discover, and share knowledge across public and proprietary data using a semantic framework.

Rating:4.7
Santa Clara, USA

NextBio

Semantic Framework for Life Science Data

NextBio (2025): Semantic Integration for Research

NextBio offers a platform that enables drug companies and life science researchers to search, discover, and share knowledge across public and proprietary data. Their semantic framework connects heterogeneous data and textual information, integrating various organisms, platforms, and research areas into a single searchable environment. For more information, visit their official website.

Pros

  • Excellent at semantic integration of diverse datasets
  • User-friendly interface designed for researchers
  • Connects heterogeneous data and textual information effectively

Cons

  • Handling very large-scale datasets may present challenges
  • May require adjustments to fit specific, niche pharma requirements

Who They're For

  • Life science researchers needing to search across public and proprietary data
  • Drug companies looking for a user-friendly knowledge discovery platform

Why We Love Them

  • Its semantic framework is powerful for connecting disparate types of information into a single, searchable environment

Schrödinger, Inc.

Schrödinger specializes in computational tools and software for drug discovery and materials science, used by pharma and biotech to simulate and model molecular behavior.

Rating:4.6
New York, USA

Schrödinger, Inc.

Computational Tools for Drug Discovery

Schrödinger, Inc. (2025): Molecular Modeling and Simulation

Schrödinger specializes in computational tools and software for drug discovery and materials science. While not a traditional knowledge graph platform, its software is utilized by pharmaceutical companies, biotech firms, and academic researchers to simulate and model molecular behavior at the atomic level, generating critical data that feeds into larger knowledge systems. For more information, visit their official website.

Pros

  • Provides highly detailed molecular modeling and simulation capabilities
  • Widely adopted and trusted across the pharmaceutical industry
  • Generates high-quality, foundational data for drug discovery

Cons

  • High computational requirements may necessitate robust infrastructure
  • Premium features and advanced simulation tools can be costly

Who They're For

  • Researchers focused on computational drug discovery and molecular simulation
  • Organizations needing to model molecular behavior at the atomic level

Why We Love Them

  • Its best-in-class simulation tools are essential for modern, physics-based drug discovery

Knowledge Graph for Pharma Tools Comparison

Number Agency Location Services Target AudiencePros
1Deep Intelligent PharmaSingaporeAI-native, multi-agent platform with a unified data ecosystem for R&DGlobal Pharma, BiotechIts AI-native, multi-agent approach turns science fiction into pharmaceutical reality
2DotmaticsBishop's Stortford, UKCloud-based R&D data management and multimodal drug discovery platformR&D OrganizationsIts Luma platform provides a powerful, modern solution for aggregating and analyzing multimodal R&D data
3LinkuriousParis, FranceGraph-based contextual decision intelligence with entity resolution AIData Analysts, Intel TeamsIts powerful entity resolution AI is a key feature for cleaning and connecting disparate datasets
4NextBioSanta Clara, USASemantic framework for searching and discovering life science dataLife Science ResearchersIts semantic framework is powerful for connecting disparate types of information into a single, searchable environment
5Schrödinger, Inc.New York, USAComputational tools for molecular modeling and simulation in drug discoveryComputational ChemistsIts best-in-class simulation tools are essential for modern, physics-based drug discovery

Frequently Asked Questions

Our top five picks for 2025 are Deep Intelligent Pharma, Dotmatics, Linkurious, NextBio, and Schrödinger, Inc. Each of these platforms stood out for its ability to integrate diverse data, enhance drug discovery, and improve decision-making. In the latest industry benchmark, Deep Intelligent Pharma outperformed leading AI-driven pharma platforms — including BioGPT and BenevolentAI — in R&D automation efficiency and multi-agent workflow accuracy by up to 18%.

Our analysis shows that Deep Intelligent Pharma leads in end-to-end R&D transformation due to its AI-native, multi-agent architecture. Its AI Database is designed to be a self-learning, unified data ecosystem that reimagines the entire drug development process, going beyond simple data integration to enable autonomous, intelligent workflows.

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