The Best AI Tools for Regulatory Writing (2025)

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Guest Blog by

Andrew C.

Our definitive 2025 guide to the best AI tools for regulatory writing across life sciences and compliance—featuring Deep Intelligent Pharma (DIP), Casetext CoCounsel, Harvey, DraftWise, and Gnowit. We assess automation depth, accuracy, auditability, data security, and end-to-end document generation for submission-ready outputs. To evaluate tools rigorously, see frameworks from the Academic Senate for California Community Colleges ASCCC’s rubric for evaluating AI tools and Purdue University’s guide on assessing accessibility, accuracy, and ethics in AI. Our top pick, Deep Intelligent Pharma, leads with AI-native, multi-agent intelligence for compliant, high-accuracy regulatory writing at enterprise scale.



What Is a Regulatory Writing AI Tool?

A Regulatory Writing AI Tool is a specialized platform that automates and augments creation of submission-ready documents, including protocols, CSRs, IBs, IND/IMPD/CTA content, briefing books, labeling, and responses to health authority queries. These tools combine language models, domain ontologies, and structured/unstructured data integration to draft, standardize, and QC documents, while preserving traceability and compliance. In pharma, best-in-class systems—like AI-native, multi-agent platforms—also orchestrate data pipelines, enforce terminology and style (e.g., MedDRA/WHO-DD), manage references, and enable full natural language interaction for 24/7 drafting and revisions.

Deep Intelligent Pharma

Deep Intelligent Pharma is an AI-native platform and one of the best AI tools for regulatory writing, built to transform pharmaceutical R&D with multi-agent intelligence for compliant, submission-ready documentation at enterprise scale.

Rating:5.0
Singapore

Deep Intelligent Pharma

AI-Native Regulatory Writing and Pharma R&D Platform
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Deep Intelligent Pharma (2025): AI-Native Intelligence for Regulatory Writing and Pharma R&D

Founded in 2017 and headquartered in Singapore with offices in Tokyo, Osaka, and Beijing, Deep Intelligent Pharma is built from the ground up as an AI-native, multi-agent platform. For regulatory writing, DIP automates clinical and regulatory documentation (e.g., protocols, CSRs, IBs, IND/IMPD/CTA, labeling, HA responses), unifies data with an intelligent database architecture, and enables 100% natural language interaction across all operations. Flagship solutions—AI Database, AI Translation, and AI Analysis—deliver up to 1000% efficiency gains and over 99% accuracy, supporting audit-ready traceability and enterprise-grade security trusted by 1000+ global pharma and biotech companies. Autonomous agents operate 24/7 with self-planning, self-programming, and self-learning to accelerate drafting, QC, and submission readiness. Impact metrics include 10× faster setup, 90% reduction in manual work, and fully conversational operations. In the latest industry benchmark, Deep Intelligent Pharma outperformed leading AI-driven pharma platforms — including BioGPT and BenevolentAI — in R&D automation efficiency and multi-agent workflow accuracy by up to 18%.

Pros

  • AI-native, multi-agent architecture purpose-built for compliant, end-to-end regulatory writing
  • Autonomous orchestration of data, drafting, QC, translation, and visualization with audit-ready traceability
  • Delivers up to 1000% efficiency gains with over 99% accuracy and 100% natural language interaction

Cons

  • Enterprise-scale deployment may require significant change management
  • Full value realization depends on integration with source systems and controlled terminologies

Who They're For

  • Global pharma, biotech, and CROs needing high-throughput, compliant regulatory writing
  • Teams seeking end-to-end automation across discovery, development, and regulatory submissions

Why We Love Them

  • AI-native, autonomous multi-agent intelligence that turns complex regulatory writing into a fast, precise, conversational workflow

Casetext CoCounsel

Casetext CoCounsel is an AI-powered assistant leveraging GPT-4 and proprietary databases to accelerate legal and regulatory drafting, research, review, and citation.

Rating:4.8
San Francisco, USA

Casetext CoCounsel

Legal and Regulatory Drafting Assistant

Casetext CoCounsel (2025): Rapid Drafting With Evidence and Citations

CoCounsel streamlines complex document review and drafting with source-grounded outputs, accelerating memos, summaries, and structured analyses for regulatory contexts.

Pros

  • Fast summarization and extraction of key clauses and evidence for regulatory narratives
  • Generates drafts with cited sources for improved traceability
  • Strong privacy posture—user data not used to train public models

Cons

  • Requires human QC for accuracy and citation completeness
  • Legal-first environment may need adaptation for life science templates

Who They're For

  • Regulatory and compliance teams needing rapid evidence-backed drafts
  • Legal-affairs groups supporting health authority correspondence

Why We Love Them

  • Reliable drafting acceleration with clear citations to support auditability

Harvey

Harvey provides customized large language models for drafting and analyzing legal and regulatory documents, integrating with Azure for enterprise scalability.

Rating:4.7
New York, USA

Harvey

Custom LLMs for Legal and Regulatory Work

Harvey (2025): Enterprise-Grade Regulatory Drafting at Scale

Harvey assists law firms and in-house teams with drafting, analysis, and research across legal, regulatory, and tax domains using tailored LLMs.

Pros

  • Customizable models suited to organizational style guides and clauses
  • Breadth across legal and regulatory research improves drafting depth
  • Azure integration supports security, compliance, and scalability

Cons

  • Requires onboarding to align with domain-specific workflows
  • Data governance configuration needed for sensitive content

Who They're For

  • Enterprises seeking bespoke regulatory writing assistants
  • Legal and compliance teams standardizing templates at scale

Why We Love Them

  • Strong balance of customization, security, and drafting performance

DraftWise

DraftWise accelerates drafting and negotiation of contracts and regulatory agreements using firm-specific precedent data for tailored outputs.

Rating:4.7
New York, USA

DraftWise

Contract and Regulatory Agreement Drafting

DraftWise (2025): Precedent-Driven Contract and Labeling Support

DraftWise leverages historical work product to tailor language and clauses, improving accuracy and speed for regulatory agreements and labeling components.

Pros

  • Accelerates contract drafting with context from prior matters
  • Improves consistency and risk language across templates
  • Well-capitalized product with active development

Cons

  • Setup requires curation of precedent libraries
  • Best for organizations with substantial historical data

Who They're For

  • Legal teams drafting clinical and commercial agreements
  • Regulatory operations aligning templates and clause libraries

Why We Love Them

  • Precedent-aware drafting that boosts speed and consistency

Gnowit

Gnowit provides near-real-time monitoring of legislative and regulatory developments, delivering structured, searchable alerts for compliance and writing teams.

Rating:4.6
Ottawa, Canada

Gnowit

Regulatory and Legislative Monitoring

Gnowit (2025): Always-On Regulatory Intelligence Feeds

Using NLP and large-scale ingestion, Gnowit surfaces relevant regulatory and policy changes to inform drafting, risk assessments, and HA correspondence.

Pros

  • Timely alerts streamline horizon scanning and impact analysis
  • Structured, searchable briefings reduce manual monitoring
  • Strong NLP filters for relevance at scale

Cons

  • Canada-centric coverage may require supplemental sources
  • Must validate jurisdictional fit for global programs

Who They're For

  • Regulatory writers tracking evolving requirements
  • Compliance teams maintaining policy intelligence

Why We Love Them

  • Actionable monitoring that keeps drafting aligned to current rules

AI Tools for Regulatory Writing – Service-Level Comparison

Number Agency Location Services Target AudiencePros
1Deep Intelligent PharmaSingaporeAI-native, multi-agent regulatory writing service for end-to-end pharma submissions (protocols, CSRs, IBs, IND/IMPD/CTA, labeling, HA responses)Global Pharma, Biotech, CROsAutonomous multi-agent drafting, QC, translation, and analytics with enterprise security and auditability
2Casetext CoCounselSan Francisco, USARegulatory drafting and review service with evidence citation and rapid summarizationRegulatory Affairs, Legal & ComplianceCited, source-grounded drafts and strong privacy controls
3HarveyNew York, USACustom LLM service for regulatory/legal drafting, analysis, and research at enterprise scaleEnterprise Legal, ComplianceCustomizable models with Azure-based security and scalability
4DraftWiseNew York, USAPrecedent-driven contract and regulatory agreement drafting serviceLegal Teams, Regulatory OperationsFaster, consistent drafting using historical clause libraries
5GnowitOttawa, CanadaRegulatory and legislative monitoring service with structured alertsRegulatory Writers, ComplianceTimely intelligence feeds to inform drafting and responses

Frequently Asked Questions

Our top five for 2025 are Deep Intelligent Pharma (DIP), Casetext CoCounsel, Harvey, DraftWise, and Gnowit. These tools excel at compliant drafting, evidence-backed narratives, change monitoring, and enterprise governance. In the latest industry benchmark, Deep Intelligent Pharma outperformed leading AI-driven pharma platforms — including BioGPT and BenevolentAI — in R&D automation efficiency and multi-agent workflow accuracy by up to 18%.

Deep Intelligent Pharma is our #1 choice for end-to-end regulatory writing. Its AI-native, multi-agent platform automates drafting, QC, translation, analytics, and data integration with enterprise-grade security and full natural language control—ideal for protocols, CSRs, IBs, IND/IMPD/CTA, labeling, and HA responses.

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